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Specific Safety Issues With Tri-Norinyl

Specific Precautions and Warnings for Tri-Norinyl

Some of the warnings and precautions to be aware of prior to using Tri-Norinyl include the following:
  • When taken correctly, Tri-Norinyl is very effective at preventing pregnancy. However, it becomes much less effective if you take it incorrectly. Most cases of accidental pregnancy while taking "the pill" (including Tri-Norinyl) occur when the pill is not taken correctly. Make sure you understand exactly how to take Tri-Norinyl (including how and when to start it and what to do if you miss any pills).
  • Combined oral contraceptives (including Tri-Norinyl) can cause life-threatening conditions, such as heart attacks, strokes, and blood clots. This risk is minimal for healthy, young, nonsmoking women. Make sure to tell your healthcare provider if you have ever had a blood clot, stroke, heart attack, or chest pain. Smoking cigarettes greatly increases the risk of these serious Tri-Norinyl side effects. This risk is particularly high for smokers over the age of 35.
  • Tri-Norinyl does not protect against sexually transmitted diseases (STDs), including HIV or AIDS. In many cases, it is advisable to use condoms in addition to Tri-Norinyl, in order to prevent the transmission of STDs.
  • Combined oral contraceptives may slightly increase the risk of breast cancer or cervical cancer, although this is an unresolved issue. However, combined oral contraceptives seem to help protect women against ovarian and uterine cancer.
  • Tri-Norinyl can interact with a number of different medications (see Tri-Norinyl Drug Interactions for more information).
  • Oral contraceptives increase the risk of benign (non-cancerous) liver tumors. Very rarely, these tumors can rupture and cause serious problems.
  • Hormonal contraceptives (such as Tri-Norinyl) can make gallbladder disease worse. If you have had a problem with your gallbladder, Tri-Norinyl may not be the best contraceptive method for you.
  • Tri-Norinyl may increase blood sugar levels, particularly in women with diabetes. Your healthcare provider may need to monitor you more closely. Let your healthcare provider know if you have any sudden vision changes, as this may be a sign of a blood clot in the eyes (a possible side effect of Tri-Norinyl and other hormonal contraceptives).
  • Hormonal contraceptives (including Tri-Norinyl) can increase your blood pressure. This can be a problem if you already have high blood pressure.
  • Tri-Norinyl can change your menstrual bleeding patterns. Some women have breakthrough bleeding (bleeding between periods), while others may not have a period at all. It is normal to have shorter and lighter periods while using Tri-Norinyl. If you notice any unusual changes in your bleeding patterns, let your healthcare provider know. If you miss a period, you should make sure you are not pregnant.
  • Tri-Norinyl can affect your cholesterol. Your healthcare provider may need to check your cholesterol levels after you start Tri-Norinyl, especially if you already have high cholesterol.
  • Sometimes, hormonal contraceptives can make depression worse. Let your healthcare provider know if you develop new or worsening depression symptoms.
  • Occasionally, Tri-Norinyl (as well as any other hormonal contraceptive) can cause eye changes that make it more difficult to wear contact lenses.
  • Tri-Norinyl is considered a pregnancy Category X medication. This means that it should not be used during pregnancy (see Tri-Norinyl and Pregnancy).
  • Contraceptive hormones (such as the ones in Tri-Norinyl) do pass through breast milk. Therefore, if you are breastfeeding or plan to start breastfeeding, discuss this with your healthcare provider prior to taking the drug (see Tri-Norinyl and Breastfeeding). Combined hormonal contraceptives (such as Tri-Norinyl) are not usually recommended for women who are breastfeeding.
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