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More Info on Stavudine

What If I Overdose on Stavudine?

People who take too much stavudine may experience the following problems:
  • Nerve problems (which can cause burning, numbness, tingling, or other unusual sensations in the hands or feet)
  • Liver damage.
If you happen to overdose on stavudine, seek immediate medical attention.
(Click Zerit Overdose for more information.)

Stavudine: Storage Methods

Stavudine capsules should be stored at room temperature, away from moisture and heat. Stavudine oral solution should be kept in the refrigerator and is good for one month after it is mixed by your pharmacist (after one month, you must dispose of any unused stavudine oral solution). Keep stavudine capsules and stavudine oral solution in an airtight container.
Keep stavudine and all other medications out of the reach of children.

What Should I Do If I Miss a Dose of Stavudine?

It is very important that you do not miss stavudine doses. If you do not take your stavudine as scheduled, take the missed dose as soon as possible. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Be sure to tell your healthcare provider if you are having trouble remembering to take your HIV medications.

How Does Stavudine Work?

Stavudine is part of a group of medications known as nucleoside reverse transcriptase inhibitors (NRTIs). NRTI medications work by blocking a process that the HIV virus needs in order to multiply.
HIV (the human immunodeficiency virus) is the virus that is responsible for AIDS. Like other viruses, HIV must use a person's own cells to reproduce. However, HIV is different than other viruses because it must first convert its genetic material from RNA to DNA. It is the DNA genes that allow HIV to multiply.
HIV converts its genetic material into DNA by using a special protein called the reverse transcriptase enzyme. To create DNA, this enzyme uses several different molecular building blocks.
Stavudine works by tricking reverse transcriptase into thinking it is one of these molecular building blocks. However, it is just different enough that when used to create DNA, stavudine actually stops the DNA from being made. Without DNA, HIV cannot multiply.
Stavudine is not a cure for HIV or AIDS. Although it can help stop HIV from infecting uninfected cells in the body, it does not help cells that have already been infected with the virus.

Stavudine for Treating HIV/AIDS

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