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Safyral Drug Interactions

If you take ibuprofen, heparin, phenytoin, or certain other medications, be aware that these drugs can interfere with Safyral. Interactions with this birth control pill have been known to decrease Safyral's effectiveness, which increases your risk of pregnancy. An increased risk of side effects is also possible. Before taking this birth control pill, tell your doctor about any other medications you are taking.

An Introduction to Interactions With Safyral

Safyral™ (drospirenone/ethinyl estradiol/levomefolate calcium) can potentially react with several other medicines. Some of the drugs that may lead to interactions with Safyral include:
 
 
  • Aminoglutethimide (Cytadren®)
  • Angiotensin II receptor blockers (ARBs), such as:

 

  
  • Antibiotics
  • Aprepitant (Emend®)
  • Atorvastatin (Lipitor®) or combination medications that contain atorvastatin (Caduet®, Liptruzet™)
  • Barbiturates, such as:
     
    • Amobarbital (Amytal®)
    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Secobarbital (Seconal®)
 
 
 
  • Phenytoin (Dilantin®, Phenytek®) or fosphenytoin (Cerebyx®)
  • Potassium products, such as:
     
    • Potassium chloride (K-Dur®, Klor-Con®, Micro-K®)
    • Potassium citrate (Urocit-K®, Polycitra-K®)
    • Potassium gluconate
    • Potassium phosphate (Neutra-Phos-K®, K-Phos®)
    • Salt substitutes (used to flavor food)
 
 
 
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Safyral Birth Control Information

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