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Safyral and Pregnancy

As a pregnancy Category X medication, Safyral (drospirenone/ethinyl estradiol/levomefolate calcium) should not be taken if you are expecting. However, it is not likely to cause problems if accidentally taken early in the pregnancy. If you know you are pregnant, stop taking Safyral immediately and contact your healthcare provider for more information.

Can Pregnant Women Take Safyral?

Safyral™ (drospirenone/ethinyl estradiol/levomefolate calcium) is a prescription oral contraceptive, also known as a birth control pill. As with all oral contraceptives, Safyral should not be used intentionally during pregnancy.
Interestingly, Safyral is one of only a few birth control pills containing folate, a B vitamin. Since no form of birth control (including Safyral) is 100 percent effective (other than abstinence, of course), some women will get pregnant while taking Safyral. The folate helps to prevent birth defects.

What Is Pregnancy Category X?

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category X is given to medications that should not be used during pregnancy. Often, this is due to serious problems that could potentially occur, such as birth defects or miscarriages.
Even though Safyral is a pregnancy Category X medication, it is not likely to cause any problems if accidentally used during early pregnancy. In animal studies, drospirenone (one of the hormones in Safyral) increased the risk of miscarriages and slow fetal development.
When drospirenone was given to animals in late pregnancy, however, male offspring developed feminine characteristics, probably because drospirenone works against testosterone and other male hormones. It is not known if these problems would also occur in humans.
Pregnancy and Pain

Safyral Birth Control Information

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