• Depression or other emotional changes
• Migraines
• Breast lumps
• Heavy vaginal bleeding between periods (light bleeding or spotting is normal)
• High blood pressure (hypertension)
• High cholesterol
• Signs of a blood clot in the leg, such as:

• Pain in the calf
• Leg cramps
• Leg or foot swelling

• Signs of a blood clot in the lung, such as:

• Shortness of breath
• Sharp chest pain
• Coughing up blood

• Chest pain or heaviness, which may be signs of a heart attack
• Sudden loss of vision or vision changes, which can be a sign of a blood clot in the eye
• Signs of a stroke, such as:

• Vision or speech changes
• Weakness or numbness in an arm or leg
• Severe headache

• Signs of liver damage, such as:

• Yellow eyes or skin (jaundice)
• Dark urine
• Upper-right abdominal pain

• Signs of an allergic reaction, such as:

• Unexplained rash
• Hives
• Itching
• Unexplained swelling
• Wheezing
• Difficulty breathing or swallowing.