Ortho Tri-Cyclen Lo Drug Interactions (Cont.)

Ortho Tri-Cyclen Lo Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Ortho Tri-Cyclen Lo is combined with any of the drugs listed above.
 
Aminoglutethimide (Cytadren)
Aminoglutethimide may make Ortho Tri-Cyclen Lo less effective, possibly increasing your risk of pregnancy. Talk with your healthcare provider before using these medications together. You may need to use a backup method of contraception, such as condoms.
 
Antibiotics
There have been reports of accidental pregnancy occurring in women taking birth control pills and certain antibiotics. However, it is still uncertain how significant the interaction between birth control pills and antibiotics may be. Some antibiotics may be more likely to cause problems than others. Ask your healthcare provider if you need a backup method of contraception any time you take an antibiotic.
 
Aprepitant (Emend)
Aprepitant may make Ortho Tri-Cyclen Lo less effective, perhaps increasing your chance of pregnancy. Talk with your healthcare provider before using these medications together. You may need to use a backup method of contraception.
 
Atorvastatin (Lipitor)
Atorvastatin may increase the level of Ortho Tri-Cyclen Lo in your blood, which may increase your risk of Ortho Tri-Cyclen Lo side effects. Check with your healthcare provider before taking these medications together.
 
Barbiturates
Barbiturates may cause your body to metabolize the hormones in Ortho Tri-Cyclen Lo too quickly, possibly increasing your risk of pregnancy. Ask your healthcare provider if you should use a different method of contraception while taking a barbiturate.
 
Cyclosporine (Gengraf, Neoral, Sandimmune)
Ortho Tri-Cyclen Lo may increase the level of cyclosporine in your blood, possibly increasing the chance of side effects of cyclosporine. Talk with your healthcare provider before taking these medications together. Your cyclosporine dose may need to be reduced, or you may need to switch to a different method of contraception.
(Ortho Tri-Cyclen Lo Drug Interactions Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;