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Ortho-Novum Drug Interactions

Talk to your healthcare provider before combining certain medications with Ortho-Novum. Drug interactions may occur if it is taken with antibiotics, several seizure medications, and certain barbiturates. Some of these interactions can decrease the effectiveness of Ortho-Novum, possibly increasing the risk of pregnancy. If you are unsure about any particular Ortho-Novum drug interaction, use a backup method of contraception until you can talk to your healthcare provider.

An Introduction to Ortho-Novum Drug Interactions

Ortho-Novum® can potentially interact with numerous other medicines. Many of these interactions can be severe enough to cause accidental pregnancy, and a backup method of birth control may be recommended.
Many medications interact with Ortho-Novum, so it is a good idea to make sure that all of your healthcare providers know you are taking Ortho-Novum. Anytime you start a new medication, check with your healthcare provider about possible drug interactions with Ortho-Novum. Some of the medicines that may lead to interactions include:
  • Aminoglutethimide (Cytadren®)
  • Antibiotics
  • Aprepitant (Emend®)
  • Barbiturate medications, such as:
    • Amobarbital (Amytal®)
    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Primidone (Mysoline®)
    • Secobarbital (Seconal®)
  • Protease inhibitors, such as:
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