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More Medicines That React With Ortho-Novum

Dexamethasone (Decadron)
Combining dexamethasone with Ortho-Novum may increase your risk of pregnancy. Check with your healthcare provider before taking these medications together, as you may need to use a backup method of birth control.
Modafinil (Provigil)
Modafinil can make Ortho-Novum less effective, perhaps increasing your risk of pregnancy. Talk with your healthcare provider, as you may need to use a backup method of contraception.
Numerous Seizure Medications
Some seizure medications may cause your body to metabolize the hormones in Ortho-Novum too quickly, potentially increasing your risk of pregnancy. Ask your healthcare provider if you should use a different method of contraception while taking a seizure medication.
Protease Inhibitors
Using Ortho-Novum with a protease inhibitor may increase your risk of pregnancy and can make the protease inhibitor less effective. Talk with your healthcare provider before combining these medications.
Selegiline (Eldepryl, Emsam, Zelapar)
The hormones in Ortho-Novum may increase the level of selegiline in your blood, possibly increasing your risk of side effects. Your healthcare provider may need to lower your selegiline dosage or may recommend an alternate form of contraception.
St. John's Wort
St. John's wort (a commonly used herbal supplement) may decrease the effectiveness of Ortho-Novum, potentially increasing the chance of pregnancy. In general, you should not take St. John's wort while using Ortho-Novum.

Final Thoughts on Ortho-Novum Drug Interactions

It is possible that not every drug interaction was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the Ortho-Novum drug interactions that may apply to you.
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