How Does Nevirapine Work?
Nevirapine belongs to a group of
HIV medications known as non-nucleoside reverse transcriptase inhibitors (NNRTIs). These medicines work by blocking a process that the HIV virus needs in order to multiply.
HIV (human immunodeficiency virus) is the virus that causes
AIDS. Like other viruses, HIV must use a person's own cells to reproduce. However, HIV is a little different from other viruses because it must first convert its genetic material from RNA to DNA. It is the DNA genes that allow HIV to multiply.
HIV converts its genetic material by using a special protein called the reverse transcriptase enzyme. To create DNA, this enzyme uses several different protein building blocks.
Nevirapine works by attaching to the reverse transcriptase enzyme, stopping it from making DNA. Without DNA, HIV cannot multiply. Nevirapine is not a cure for HIV or AIDS. It can help stop HIV from infecting uninfected cells in the body, but it does not help cells that have already been infected with the virus.
Nevirapine Use in Children
Nevirapine is approved for use in children as young as 15 days old. Talk with your child's healthcare provider about the benefits and risks of using nevirapine in children.
Off-Label Nevirapine Uses
On occasion, your healthcare provider may recommend nevirapine for treating something other than HIV infection and AIDS. This is called an "
off-label" use. At this time, nevirapine is used off-label to prevent HIV infection in people exposed to the HIV virus (such as a healthcare worker who comes in contact with a contaminated needle stick). This is called postexposure prophylaxis (PEP).
Previous
Add this article to your Favorites
Email this article
Print