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MetroGel-Vaginal Drug Interactions

It is possible for dangerous reactions to occur if you use certain drugs while undergoing treatment with MetroGel-Vaginal. Interactions may occur if this vaginal gel is combined with products like warfarin, lithium, and even alcohol. To help minimize your risk for problems, make sure your healthcare provider is aware of all medications, vitamins, and supplements you are taking.

An Overview of Interactions With MetroGel-Vaginal

MetroGel-Vaginal® (metronidazole vaginal gel) may react with a few other medications. Some of the drugs that may interact with MetroGel-Vaginal include but are not limited to:
 
 

MetroGel-Vaginal Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when MetroGel-Vaginal is combined with any of the drugs listed above.
 
Alcohol
The standard advice is that people taking metronidazole products should not drink alcohol. However, this interaction is probably less likely to occur when metronidazole is applied vaginally, as it is with MetroGel-Vaginal. However, there is some uncertainty about the validity of this interaction (see Metronidazole and Alcohol).
 
Amprenavir
Combining MetroGel-Vaginal with amprenavir oral solution (but not the other forms of amprenavir) can cause a dangerous interaction with metronidazole, the active ingredient in MetroGel-Vaginal. However, it is unclear if this interaction applies to the vaginal formulations, as only a small amount of the medication is absorbed into the bloodstream. Check with your healthcare provider before using these drugs together.
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MetroGel-Vaginal Information

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