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MetroGel-Vaginal and Breastfeeding

The active ingredient in MetroGel-Vaginal (metronidazole vaginal gel) does pass through breast milk. Although there have not been any significant side effects reported in infants whose mothers used this drug, there is some concern that metronidazole may increase the risk for certain types of cancer. Due to this risk, the manufacturer recommends that women not use MetroGel-Vaginal while breastfeeding.

Can Breastfeeding Women Use MetroGel-Vaginal?

The active ingredient in MetroGel-Vaginal® (metronidazole vaginal gel) passes through breast milk in humans. There is some concern about the carcinogenic (cancer-causing) potential of metronidazole, especially when young children may be exposed.
If you are breastfeeding a child or plan to start, you should talk with your healthcare provider before using this medicine. The manufacturer recommends that women not use MetroGel-Vaginal while breastfeeding.

More Information on Metronidazole and Breastfeeding

Studies have shown that metronidazole, the active ingredient in MetroGel-Vaginal, passes through breast milk. No significant side effects in infants have been reported due to maternal use of the drug. However, there is a theoretical risk of childhood or even adult cancer due to metronidazole exposure through breast milk. Metronidazole was shown to increase the risk for certain cancers in mice and rats; it is unknown if the same is true for humans.
Keep in mind that the levels found in breast milk after using metronidazole vaginal products such as MetroGel-Vaginal are much lower than would be found after taking metronidazole by mouth or intravenously.
If your healthcare provider recommends using MetroGel-Vaginal while breastfeeding, make sure to watch for any potential problems, especially diarrhea, thrush, or yeast infections, which have been reported in infants exposed to metronidazole through breast milk.
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MetroGel-Vaginal Information

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