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Drugs That React With Medroxyprogesterone

Medroxyprogesterone Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when medroxyprogesterone is combined with any of the drugs listed above.
 
Antibiotics
There have been reports of women becoming pregnant while taking antibiotics in combination with hormonal birth control, suggesting antibiotics may decrease the effectiveness hormonal contraceptives. At this time, it is not known if medroxyprogesterone interacts with antibiotic medications. However, if you are using medroxyprogesterone to prevent pregnancy, you may want to use a backup method of birth control while taking an antibiotic.
 
Antiseizure Medications
Injectable medroxyprogesterone can cause a loss of bone density, especially when used for an extended period. Certain antiseizure medications (also called antiepileptics) can also negatively affect bone health. Thus, taking these medications together may further increase your risk for bone loss, osteoporosis, and fractures. Talk to your healthcare provider about this potential interaction before taking medroxyprogesterone with an antiseizure drug.
 
Corticosteroids
Injectable medroxyprogesterone can cause a loss of bone density, especially when used for an extended period. Corticosteroid medications can also affect bone health. Thus, taking these medications together may further increase your risk for bone loss, osteoporosis, and fractures. Talk to your healthcare provider about this potential interaction before taking these drugs together.
 
Cyclosporine
Medroxyprogesterone may increase the level of cyclosporine in your blood, potentially increasing your risk for side effects. Your healthcare provider may choose to monitor you more closely, and may give you a lower cyclosporine dosage, if you take these medications together.
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Medroxyprogesterone Drug Information

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