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Medroxyprogesterone and Breastfeeding

Medroxyprogesterone (Provera, Depo-Provera, depo-subQ Provera 104) does pass through breast milk; however, it is usually considered safe for nursing women and their infants. If you are breastfeeding, it's generally recommended to wait six weeks after giving birth before starting medroxyprogesterone as your form of birth control. Talk to your healthcare provider to make sure this medication is suitable for your particular situation.

Is Medroxyprogesterone Safe for Breastfeeding Women?

Medroxyprogesterone is a prescription hormone medication. It comes in the form of a tablet (Provera®) or an injection. The injectable forms are sold as medroxyprogesterone intramuscular injection (Depo-Provera®) and medroxyprogesterone subcutaneous injection (depo-subQ Provera 104®).
Medroxyprogesterone is known to pass through breast milk, but is generally considered safe for use in women who are nursing.

More Information on Breastfeeding and Medroxyprogesterone

As mentioned, medroxyprogesterone is known to pass through breast milk in small amounts. The manufacturer of the oral form recommends the medication not be used while breastfeeding. However, studies indicate that medroxyprogesterone in breast milk will not harm a nursing infant. In addition, it does not affect the amount or quality of the breast milk produced.
If hormonal birth control is going to be used while breastfeeding, progestin-only birth control (like medroxyprogesterone injection) is preferred over birth control that contains estrogen. This is because estrogen can increase a woman's risk for a serious blood clot in the four weeks after childbirth and can decrease breast milk supply.
It is generally recommended that women wait to use medroxyprogesterone injection until six weeks after giving birth. This helps reduce the amount of the medicine passed to the baby in the early weeks of life.
(Click Breastfeeding and Birth Control for more information.)
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