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Effects of Medroxyprogesterone on Memory

The prescription drug medroxyprogesterone (Provera®, Depo-Provera®, depo-subQ Provera 104®) has many effects within the body. Unfortunately, the effects of medroxyprogesterone do not extend to the prevention of memory loss associated with dementia. In fact, studies have shown that using estrogen in combination with medroxyprogesterone (known as combination hormone therapy, or combination HT) actually increases the risk for dementia.
Because of these risks, combination hormone therapy should only be used at the lowest effective dose for the shortest time necessary.
(For more information, click Medroxyprogesterone Warnings and Precautions. This article lists other important safety warnings to be aware of before using this product, including details on who should avoid it entirely.)
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