The following sections explain in detail the potentially negative interactions that can occur when Ortho-Novum is combined with any of the drugs listed above. If you are unsure about any particular drug interaction, it is a good idea to use a backup method of birth control until you can speak with your healthcare provider.
Taking Ortho-Novum with aminoglutethimide may increase your risk of unintentional pregnancy. Talk with your healthcare provider before using these medications together. You may need to use a backup method of contraception, such as condoms.
There have been reports of accidental pregnancy occurring in women taking birth control pills with certain antibiotics. However, the significance of this interaction is still uncertain. Some antibiotics are more likely to cause problems than others. Any time you take an antibiotic, make sure to ask your healthcare provider if you need to use a backup method of contraception.
Aprepitant can make Ortho-Novum less effective, perhaps increasing your chance of pregnancy. Talk with your healthcare provider before using these medications together. You may need to use a backup method of contraception.
Barbiturates may cause your body to metabolize the hormones in Ortho-Novum too quickly, possibly increasing your risk of pregnancy. Ask your healthcare provider if you should use a different method of contraception while taking a barbiturate.
Cyclosporine (Gengraf, Neoral, Sandimmune)
Ortho-Novum may increase the level of cyclosporine in your blood, possibly increasing the chance of side effects of cyclosporine. Talk with your healthcare provider before taking these medications together. You may need a lower cyclosporine dose, or you may need to switch to a different method of contraception.
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