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Ogestrel Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Ogestrel is combined with any of the drugs listed above. It is important to note that if a backup method of contraception is necessary, you may need to use it for quite a while (often an entire cycle). Anytime a backup method of birth control is recommended, make sure your healthcare provider explains how long you need to use it.
 
If you do not know what to do about any particular Ogestrel drug interaction, use a backup method of birth control until you can check with your healthcare provider, just to be safe.
 
Aminoglutethimide (Cytadren)
Taking aminoglutethimide and Ogestrel together increases the risk of pregnancy. Do not combine these medications without first talking to your healthcare provider. You may need to use a backup method of contraception, such as condoms.
 
Antibiotics
There have been reports of accidental pregnancy occurring in women taking birth control pills with certain antibiotics. However, the significance of this interaction is still uncertain. Some antibiotics are more likely to cause problems than others. Any time you take an antibiotic, make sure to ask your healthcare provider if you need to use a backup method of contraception.
 
Aprepitant (Emend)
Aprepitant can make Ogestrel less effective, perhaps increasing your chance of pregnancy. Talk with your healthcare provider before using these medications together. You may need to use a backup method of contraception. People undergoing chemotherapy commonly use aprepitant, and it is often important for women having chemotherapy to avoid pregnancy.
 
Barbiturates
Barbiturate medications may cause your body to metabolize the hormones in Ogestrel too quickly, possibly increasing your risk of pregnancy. Ask your healthcare provider if you should use a different method of contraception while taking a barbiturate.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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