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Common Side Effects Seen With Nelfinavir

Clinical studies have not evaluated nelfinavir alone for the treatment of HIV, since nelfinavir is meant to be used along with other HIV medications. In fact, the available side effect information involves studies that used nelfinavir plus two other HIV medications. Therefore, it is difficult to determine whether these side effects are due to nelfinavir or the other HIV medications.
 
Based on these studies, the most common side effects of nelfinavir (when used with two other HIV medications) included:
 
  • Diarrhea -- in up to 20 percent of people
  • Nausea -- up to 7 percent
  • Gas -- up to 5 percent
  • Rash -- up to 3 percent.
     

Less Common Nelfinavir Side Effects

There are other less common nelfinavir side effects that can occur. These side effects occur in less than 2 percent of people taking nelfinavir. For these side effects, it is difficult to tell whether they are actually caused by nelfinavir or other factors.
 
These less common nelfinavir side effects include, but are not limited to:
 

Final Thoughts on Nelfinavir Side Effects

It is possible that you may experience some or none of the nelfinavir side effects listed in this article. Unfortunately, it can be difficult to tell whether any particular side effect (such as nausea) is actually caused by nelfinavir or other factors. Therefore, make sure to let your healthcare provider know if you develop any side effects while taking nelfinavir or if something "just does not seem right." While it may not be a side effect, your healthcare provider will be able to diagnose and treat the problem.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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