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Maraviroc is used for the treatment of HIV infection and AIDS in adults who are at least 16 years old. This prescription medication is specifically designed to treat a certain type of HIV virus, and works by preventing this virus from entering human cells. Maraviroc is approved for use only in combination with other HIV medications. There are currently no off-label maraviroc uses.

What Is Maraviroc Used For? -- An Overview

Maraviroc (Selzentry™) is a prescription medication used to treat HIV and AIDS. It belongs to a group of medications known as entry inhibitors. Maraviroc may be helpful for people who have developed HIV infections that are resistant to other types of medications. Because of the way it works, maraviroc should only be used by people who have a certain type of HIV virus, called CCR5-tropic HIV. Your healthcare provider must perform certain tests to determine which type of HIV you have before you can take maraviroc.
Acquired Immune Deficiency Syndrome (AIDS) was initially reported in the United States in 1981. Since then, it has become a significant worldwide epidemic. AIDS is caused by the human immunodeficiency virus (HIV). Initially, an HIV infection does not usually cause any obvious symptoms (see HIV Symptoms). However, by killing or damaging cells of the body's immune system, HIV will eventually begin to progressively destroy the body's ability to fight infections and certain cancers (see AIDS Symptoms).
HIV is commonly spread through sexual contact with an infected partner. Transmission also happens through contact with infected blood, which frequently occurs among IV drug users (who share needles or syringes contaminated with blood from someone infected with the virus). Women who have HIV can transmit the virus to their babies during pregnancy, birth, or breastfeeding.
Maraviroc is usually reserved for people who have tried other HIV medications without success and who are, therefore, likely to be resistant to other HIV medications. The drug is not intended to be used alone. Instead, it is used as part of an HIV "cocktail." These cocktails usually consist of three or four different HIV medications (technically known as highly active antiretroviral therapy, or HAART). Using a combination of medications helps to prevent the virus from becoming resistant to one or more of the drugs.
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Last reviewed by: Kristi Monson, PharmD;
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