It is not known exactly what to expect from an overdose of maraviroc. In animal studies, high doses of the drug increased the risk of an irregular heart rhythm (arrhythmia). If you happen to take too much maraviroc, seek immediate medical attention.
Maraviroc should be stored at room temperature, away from moisture and heat. Keep the tablets in an airtight container.
Keep this and all other medications out of the reach of children.
What Should I Do If I Miss a Dose?
It is very important that you not miss maraviroc doses. If you do not take your maraviroc as scheduled, take the missed dose as soon as possible. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Be sure to tell your healthcare provider if you are having trouble remembering to take your HIV medications.
How Does Maraviroc Work?
Maraviroc belongs to a group of HIV medications known as entry inhibitors. These medicines work by preventing the virus from entering human cells.
HIV (human immunodeficiency virus) is the virus that causes AIDS. There are different types of this virus. One type attaches to the CCR5 receptors on human cells in order to attach to and then enter the cells. This type of HIV is called CCR5-tropic HIV. There are other types of HIV that bind to other receptors. Maraviroc binds to the CCR5 receptor, preventing HIV from binding to and entering human cells. The drug is effective only for treating the CCR5-tropic HIV type; it does not work for the other types of HIV.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Selzentry [package insert]. Research Triangle Park, NC: ViiV Healthcare;2011 July.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: Approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed October 17, 2007.
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