STD Home > Important Facts About Loryna
How Does This Contraceptive Work?
Loryna is a combined oral contraceptive
, which means it is a birth control pill
that contains both an estrogen and a progestin. It prevents pregnancy primarily by stopping ovulation (the maturation and release of eggs from the ovaries).
Loryna also works to prevent pregnancy in two other, minor ways. It changes the cervical mucus (the fluid of the cervix, which is the lower, narrow part of the uterus that is connected to the vagina), making it more difficult for sperm to enter the uterus. It also alters the lining of the uterus (the endometrium), making it less receptive to an embryo.
Loryna is different from traditional birth control pills in two important ways. First, the progestin that it uses (drospirenone) is closely related to spironolactone
, a medication used as a diuretic ("water pill"). Drospirenone has anti-androgenic activity, which means that it works against testosterone and other "male" hormones. All women have a small amount of these "male" hormones that can cause acne and other problems. Also, drospirenone may increase the level of potassium in your blood, which can be a problem for some women.
Second, Loryna contains 24 active pills and 4 inactive pills (these do not contain any active ingredients). In comparison, traditional birth control pills typically have 21 active pills and 7 inactive pills. Having fewer inactive pills seems to decrease some of the bothersome symptoms that occur just before and during your period.
Effects of Loryna
The brand-name version of Loryna (Yaz®
) was shown to be an effective birth control method in a large clinical trial. In this study, for every 100 women who used the drug for a year, 1 or 2 became pregnant.
This is highly effective, compared to many other methods of contraception. For instance, up to 14 percent of women using condoms for a year will become pregnant. Studies have also shown that Yaz is effective at treating acne, as well as the symptoms of premenstrual dysphoric disorder (PMDD).