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Common Side Effects of Indinavir

Indinavir has been studied thoroughly in clinical trials. In these studies, the side effects that occur in a group of people taking the drug are documented and are then compared to side effects that occur in another group of people not taking the medicine. This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.
In these studies, the most common indinavir side effects included:
  • Abdominal pain (stomach pain) -- in up to 16.6 percent of people
  • Nausea -- up to 11.7 percent
  • Back pain -- up to 8.4 percent
  • Vomiting -- up to 8.4 percent
  • Headaches -- up to 5.4 percent
  • Diarrhea -- up to 3.3 percent
  • Dizziness -- up to 3 percent.
Other common indinavir side effects (occurring in 1 to 3 percent of people) included:
  • Weakness or fatigue
  • Fever
  • A general ill feeling (malaise)
  • Acid reflux
  • Increased or decreased appetite
  • Indigestion or heartburn
  • Yellow skin (jaundice)
  • Drowsiness
  • Cough
  • Painful urination
  • Taste changes.

Final Thoughts on Indinavir Side Effects

It is possible that you may experience some or none of the indinavir side effects listed in this article. Unfortunately, it can be difficult to tell whether any particular side effect (such as nausea) is actually caused by indinavir or other factors. Therefore, make sure to let your healthcare provider know if you develop any side effects while taking indinavir or if something "just does not seem right." While it may not be a side effect, your healthcare provider will be able to diagnose and treat the problem.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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