STD Home > Various Reactions to Etravirine

Common Side Effects

Etravirine has been studied thoroughly in clinical trials. In these studies, one group of people received etravirine, while another group was given a placebo (a "sugar pill" with no active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the placebo.
 
Clinical studies have not evaluated etravirine alone for the treatment of HIV, since etravirine is meant to be used along with other HIV medications. In fact, the available side effect information involves studies that used etravirine in combination with other HIV medications. Therefore, it is difficult to know whether these side effects are actually caused by etravirine itself or the other HIV medications.
 
Based on these studies, the most common side effects of etravirine (plus other HIV medications) included:
 
  • Rash -- in up to 10 percent of people
  • Unusual sensations (like pain, tingling, or burning) in the hands or feet -- up to 4 percent.
 
Rash occurred in up to 15 percent of children in clinical trials. Diarrhea was also reported frequently in children, although the exact percent of children who experienced diarrhea is not reported in the etravirine prescribing information.
  

Other Possible Side Effects of Etravirine

In clinical studies, other possible side effects (occurring in less than 2 percent of people) included:
 
  • Chest pain
  • A spinning sensation (vertigo)
  • Blurred vision
  • Gastroesophageal reflux disease (GERD)
  • Gas
  • An enlarged or distended stomach
  • Constipation
  • Dry mouth
  • Excessive sleepiness
  • Anemia
  • Loss of appetite
  • Confusion
  • Nervousness
  • Nightmares
  • Breast enlargement in men (gynecomastia)
  • Shortness of breath upon exertion
  • Sweating
  • Dry skin
  • Face swelling.
      
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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