STD Home > Depo-Provera Warnings and Precautions
Tell your healthcare provider if you have congestive heart failure, kidney problems, or a history of seizures before receiving injections of Depo-Provera. Other safety precautions include warnings of potential drug interactions and allergic reactions. It is also important to know that you should only use this medicine for the least amount of time necessary, as it can negatively affect the bones.
What Should I Tell My Healthcare Provider?Talk with your healthcare provider prior to receiving Depo-Provera® (medroxyprogesterone intramuscular injection) if you have:
- Unexplained vaginal bleeding
- Breast cancer, a family history of breast cancer, or a personal history of breast cancer
- An abnormal mammogram or breast problems, such as breast lumps or bleeding from your nipples
- Irregular menstrual periods
- Heart disease
- A history of a heart attack, stroke, or blood clots
- High blood pressure (hypertension)
- Liver disease, such as hepatitis, cirrhosis, or liver failure
- Kidney disease, such as kidney failure (renal failure)
- Osteoporosis or a history of fracturing a bone, or have a family history of osteoporosis
- Migraine headaches
- Seizure disorder (epilepsy)
- An alcohol problem or drink large quantities of alcohol
- Anorexia nervosa (an eating disorder)
- Any allergies, including to foods, dyes, or preservatives.
- Smoke cigarettes
- Are pregnant or thinking of becoming pregnant (see Depo-Provera and Pregnancy)
- Are breastfeeding (see Depo-Provera and Breastfeeding).