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Calcium channel blockers, antacids, and certain antibiotics or antifungals may interact negatively with atazanavir. Drug interactions such as these can lead to increased or decreased drug levels in your blood, which could cause serious side effects or reduce the effectiveness of the medicines. Other medications that can cause atazanavir drug interactions include oral contraceptives, fluticasone, tricyclic antidepressants, and other protease inhibitors.

Atazanavir Drug Interactions: An Introduction

Atazanavir sulfate (Reyataz®) can potentially interact with several other medicines. Some of the medicines that may lead to atazanavir drug interactions include:
  • Certain arrhythmia medications, such as:
  • Certain benzodiazepines, such as:


    • Bromocriptine (Parlodel®)
    • Dihydroergotamine (Migranal®)
    • Ergonovine
    • Ergotamine (Bellamine S®, Cafergot®, Ergomar®)
    • Methylergonovine (Methergine®)
    • Pergolide (Permax®)
  • Fluticasone (Flonase®, Flovent®, Veramyst®) or combination medications that contain fluticasone (Advair®)
  • Immune-suppressing medications, such as:


  • Phosphodiesterase type 5 inhibitors (PDE5 inhibitors), including:




Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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