Amprenavir should be stored at room temperature, away from moisture and heat. Keep both capsules and the oral solution in an airtight container.
Keep amprenavir and all other medications out of the reach of children.
What Should I Do If I Miss a Dose of Amprenavir?
It is very important that you not miss amprenavir doses. If you do not take your amprenavir as scheduled, take the missed dose as soon as possible. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Be sure to tell your healthcare provider if you are having trouble remembering to take your HIV medications.
How Does Amprenavir Work?
Amprenavir belongs to a group of HIV medications known as protease inhibitors. These medicines work by blocking a process that the HIV virus needs in order to multiply.
HIV (human immunodeficiency virus) is the virus that causes AIDS. Like other viruses, it must use a person's own cells to reproduce. Once inside an infected cell, the HIV virus uses the cell to make DNA, which enables it to make new HIV viruses that can spread to other cells. The DNA is made in long strands that must be clipped into shorter, usable strands using enzymes called proteases.
Amprenavir is a protease inhibitor, which means that it stops protease enzymes from clipping DNA into short strands. Because the long, unclipped DNA strands cannot be used to make new viruses, this can stop the spread of HIV to other uninfected cells.
Amprenavir is not a cure for HIV or AIDS. Although the medication can help prevent the HIV virus from infecting healthy cells in the body, it cannot help cells that have already been infected with the virus.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Agenerase Capsules [package insert]. Research Triangle Park, NC: GlaxoSmithKline;2005 May.
Agenerase Oral Solution [package insert]. Research Triangle Park, NC: GlaxoSmithKline;2005 May.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: Approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed October 11, 2007.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 7th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2005.
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