Loestrin Uses (Cont.)

How Does Loestrin Work?

As mentioned, Loestrin contains both an estrogen (ethinyl estradiol) and a progestin (norethindrone). The hormones in Loestrin prevent pregnancy primarily by stopping ovulation (the maturation and release of eggs from the ovaries).
 
Loestrin also works to prevent pregnancy in two other, less important ways. It changes the cervical mucus (the fluid of the cervix, which is the lower, narrow part of the uterus that is connected to the vagina), making it more difficult for sperm to enter the uterus. It also alters the lining of the uterus (the endometrium), making it less receptive to an embryo.
 
Unlike most birth control pills, Loestrin comes in packs with 21 tablets. It is meant to be taken every day for 21 days, followed by 7 days in between packs. Most other birth control pills have 28 tablets in each pack, but the last 7 contain no active ingredients. Either way, you get 21 days of active hormones, followed by a 7-day, hormone-free break.
 

Loestrin Uses in Children and Teens

Loestrin is approved for use in women of reproductive age. This means that it is not approved for use in girls who have not yet had their first menstrual period.
 

Off-Label Loestrin Uses

On occasion, your healthcare provider may recommend Loestrin for something other than contraception. This is called an "off-label" use. At this time, off-label Loestrin uses include treatment of the following conditions:
 
  • Acne
  • Heavy menstrual bleeding
  • Painful menstrual periods
  • Irregular menstrual periods
  • Premenstrual dysphoric disorder (PMDD).
     

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;