More Information on Interactions With Lamivudine/zidovudine
The following sections explain in detail the potentially negative interactions that can occur when
lamivudine/zidovudine is combined with any of the drugs listed above.
Atovaquone
Doxorubicin
Doxorubicin can make lamivudine/zidovudine less effective and may also increase the risk of lamivudine/zidovudine side effects. In general, these medications should not be taken together.
Fluconazole
Fluconazole may increase the level of lamivudine/zidovudine in your blood, possibly increasing your risk of side effects. Talk with your healthcare provider before using these medications together -- you may need to be monitored more closely.
Ganciclovir
Combining ganciclovir with lamivudine/zidovudine may increase your risk of lamivudine/zidovudine side effects, particularly those that affect blood cells. Your healthcare provider may need to monitor your blood counts very closely if you are taking both of these medications.
Interferon Medications
Taking an interferon medication with lamivudine/zidovudine may increase your risk of lamivudine/zidovudine side effects, particularly those that affect blood cells. Your healthcare provider may need to monitor your blood counts very closely if you are taking both of these medications.
Methadone
Methadone may increase the level of lamivudine/zidovudine in your blood, possibly increasing your risk of side effects. Talk with your healthcare provider before taking these medications together.
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