Indinavir Dosing

For most adults, the recommended indinavir dosage is 800 mg every eight hours. However, if you are taking certain medications that may interact with indinavir or have mild to moderate liver disease, indinavir dosing may need to be decreased to 600 mg every eight hours. The medicine is best absorbed into the body when it is taken one hour before or two hours after meals.

 

Indinavir Dosage: An Introduction

The dose of indinavir sulfate (Crixivan®) that your healthcare provider recommends will vary depending on a number of factors, including:
 
  • Other medical conditions you may have
  • Other medications you may currently be taking.
     
As always, do not adjust your indinavir dose unless your healthcare provider specifically instructs you to do so.
 

Indinavir Dosing for HIV and AIDS

The recommended indinavir dose for treating adults with HIV or AIDS is 800 mg (two indinavir 400 mg capsules) every eight hours. If you are taking certain other medications, a lower indinavir dose may be recommended (see Drug Interactions With Indinavir). In people with mild to moderate liver disease, the recommended dose of indinavir is 600 mg every eight hours.
 

General Information on Dosing With Indinavir

Considerations for people taking indinavir include the following:
 
  • Indinavir comes in capsule form. It is usually taken by mouth every eight hours (three times a day).
     
  • Indinavir is best absorbed into the body when it is taken one hour before or two hours after a meal. If necessary, indinavir can be taken with skim milk, juice, coffee, tea, or a light meal (such as toast with jelly).
     
  • It is important to stay hydrated while taking indinavir. You should drink at least six cups of water (48 ounces) of liquids every day.
     
  • Try to take indinavir at the same time every day to maintain an even level of the medication in your blood.
     
  • For the medication to work properly, it must be taken as prescribed. It is very important that you closely follow your healthcare provider's instructions about taking indinavir. Missing doses can increase the chance of the virus developing resistance to indinavir (making it less effective).
     
  • If you are unsure about anything related to your indinavir dosage, please talk to your doctor, nurse, or pharmacist.
     
Add this article to your Favorites     Email this article     Print
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;