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Drugs That React With Indinavir

Indinavir Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when indinavir is combined with any of the drugs listed above.
 
Alfuzosin
Indinavir should not be combined with alfuzosin, as this may increase the amount of alfuzosin in the blood to dangerous levels.
 
Bosentan
Indinavir may increase the level of bosentan in your blood. Your healthcare provider may need to lower your bosentan dosage while you are taking indinavir.
  
Certain Antibiotics or Antifungals
Combining indinavir with certain antibiotics or antifungals may increase or decrease the level of both indinavir and the antibiotic or antifungal in your blood. Check with your healthcare provider before taking indinavir with any of these medications. Indinavir should never be combined with rifampin, since rifampin may make indinavir less effective.
 
Certain Arrhythmia Medications
Indinavir may increase the level of certain arrhythmia medications in your blood, increasing the risk of dangerous side effects. Talk with your healthcare provider before taking indinavir with one of these medications. Indinavir should never be combined with amiodarone, due to the risk of life-threatening reactions.
 
Certain Benzodiazepines
Indinavir should not be combined with alprazolam, midazolam, or triazolam, due to the risk of life-threatening reactions.
 
Certain Calcium Channel Blockers
Indinavir may increase the level of certain calcium channel blockers in your blood, increasing the risk of side effects. Your healthcare provider may need to lower the dose of your calcium channel blocker.
 
Colchicine
Indinavir may increase the level of colchicine in your blood. Your healthcare provider may need to lower your colchicine dosage while you are taking indinavir.
  
Delavirdine (Rescriptor)
Delavirdine increases the level of indinavir in your blood. The lower indinavir dosage (indinavir 600 mg every eight hours) is usually recommended if you are taking delavirdine.

Indinavir Sulfate for HIV/AIDS

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