Drug Interactions With Etravirine

A number of medications can cause potentially serious drug interactions with etravirine, including erectile dysfunction medicines, certain arrhythmia drugs, diazepam, and protease inhibitors. Taking etravirine with these medications can increase or decrease the drug levels in your blood, perhaps reducing the effectiveness of these products. In order to help prevent drug interactions, you should tell your healthcare provider about all other medications you are taking.

Etravirine Interactions: An Introduction

Etravirine (Intelence™) can potentially interact with several other medicines. Some of these medicines that may lead to etravirine interactions include:
 
  • Certain antibiotics and antifungal medications, such as:

 

    • Clarithromycin (Biaxin®)
    • Fluconazole (Diflucan®)
    • Itraconazole (Sporanox®)
    • Ketoconazole (Nizoral®)
    • Posaconazole (Noxafil®)
    • Rifabutin (Mycobutin®)
    • Rifampin (Rifadin®)
    • Rifapentine (Priftin®)
    • Voriconazole (Vfend®)

 

  • Certain arrhythmia medications, including:

 

    • Amiodarone (Cordarone®)
    • Bepridil (Vascor®)
    • Disopyramide (Norpace®, Norpace CR)
    • Flecainide (Tambocor™)
    • Lidocaine (Xylocaine®)
    • Mexiletine (Mexitil®)
    • Propafenone (Rythmol®, Rythmol SR)
    • Quinidine

 

  • Certain immunosuppressants, such as:

 

    • Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
    • Sirolimus (Rapamune®)
    • Tacrolimus (Prograf®)

 

  • Certain seizure medications, including:

 

 

 

 

  • Other NNRTI medications (similar to Etravirine), such as:

 

 

  • Protease inhibitors, such as:

 

 

 

 


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(Drug Interactions With Etravirine Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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