Drug Interactions With Etonogestrel/Ethinyl Estradiol Vaginal Ring (Cont.)

Etonogestrel/Ethinyl Estradiol Vaginal Ring Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when etonogestrel/ethinyl estradiol vaginal ring is combined with any of the drugs listed above.
 
Aminoglutethimide (Cytadren)
Aminoglutethimide may make etonogestrel/ethinyl estradiol vaginal ring less effective, possibly increasing your risk of pregnancy. Talk with your healthcare provider before using these medications together. You may need to use a backup method of contraception (such as condoms).
 
Aprepitant (Emend)
Aprepitant may make etonogestrel/ethinyl estradiol vaginal ring less effective, perhaps increasing your chance of pregnancy. Talk with your healthcare provider before using these medications together. You may need to use a backup method of contraception.
 
Barbiturates
Barbiturates may cause your body to metabolize the hormones in etonogestrel/ethinyl estradiol vaginal ring too quickly, increasing your risk of pregnancy. Ask your healthcare provider if you should use a different method of contraception while taking a barbiturate.
 
Certain Seizure Medications
Some seizure medications may cause your body to metabolize the hormones in etonogestrel/ethinyl estradiol vaginal ring too quickly, increasing your risk of pregnancy. Ask your healthcare provider if you should use a different method of contraception while taking a seizure medication.
 
Cyclosporine (Gengraf, Neoral, Sandimmune)
Etonogestrel/ethinyl estradiol vaginal ring may increase the level of cyclosporine in your blood, increasing the chance of side effects of cyclosporine. Talk with your healthcare provider before taking these medications together. Your cyclosporine dose may need to be reduced, or you may need to switch to a different method of contraception.
(Drug Interactions With Etonogestrel/Ethinyl Estradiol Vaginal Ring Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;