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Precautions and Warnings With Enfuvirtide

There are several precautions and warnings with enfuvirtide to be aware of before starting the medication. These include knowing that the medication may increase your risk of developing pneumonia, allergic reactions, or reactions at the injection site. Precautions and warnings with enfuvirtide also extend to women who may be pregnant or who are considering breastfeeding.

Enfuvirtide: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking enfuvirtide (Fuzeon®) if you:
 
  • Have any allergies, including allergies to food, dyes, or preservatives
  • Are pregnant or thinking of becoming pregnant
  • Are breastfeeding.
     
You should also be sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 

Specific Precautions and Warnings With Enfuvirtide

Warnings and precautions to be aware of prior to taking enfuvirtide include the following:
 
  • Enfuvirtide should not be your only HIV medication (it should always be used in combination with other HIV drugs).
     
  • Enfuvirtide almost always causes "injection site reactions" (redness, pain, swelling, or lumps at the injection sites). However, if you develop oozing, warmth, or increased pain or redness, these could be signs of a skin infection.
     
  • In studies, enfuvirtide increased the risk of pneumonia. Contact your healthcare provider if you have signs of pneumonia, such as a cough, fever, rapid breathing, and shortness of breath.
     
  • Sometimes, the medication causes allergic reactions. Let your healthcare provider know if you have signs of an allergic reaction, such as a rash, fever, nausea and vomiting, chills, or low blood pressure (hypotension).
     
  • Enfuvirtide is not a cure for HIV or AIDS. If you have HIV or AIDS, you should always use safer sex practices, whether or not you are taking medications.
     
  • As with all HIV medications, it is important that you take enfuvirtide exactly as prescribed. Missing doses may increase the chance of the virus becoming resistant to HIV medications.
     
  • Enfuvirtide is considered a pregnancy Category B medication. This means that it is probably safe for use during pregnancy, although the full risks are not known (see Fuzeon and Pregnancy).
     
  • It is not known if enfuvirtide passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Fuzeon and Breastfeeding). It is important to understand that the HIV virus can be transmitted through breast milk and that breastfeeding is usually not recommended for women with HIV or AIDS.
     

Enfuvirtide Drug Information

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