Drug Interactions With Emtricitabine and Tenofovir (Cont.)

Emtricitabine and Tenofovir Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when emtricitabine and tenofovir is combined with any of the drugs listed above.
 
Adefovir
Adefovir may interfere with the kidneys' ability to remove emtricitabine and tenofovir from the blood. This could lead to increased blood levels of emtricitabine and tenofovir and increased risk of side effects of emtricitabine and tenofovir. Check with your healthcare provider before taking these medications together.
 
Acyclovir
Acyclovir may interfere with the kidneys' ability to remove emtricitabine and tenofovir from the blood. This could lead to increased blood levels of emtricitabine and tenofovir and increased risk of side effects. Check with your healthcare provider before taking these medications together.
 
Atazanavir
Taking atazanavir and emtricitabine and tenofovir together may affect the level of both medications in your blood. Your healthcare provider may need to adjust your doses of these medications to prevent interactions from occurring.
 
Certain Protease Inhibitors
Some protease inhibitors may increase the level of emtricitabine and tenofovir in your blood, and emtricitabine and tenofovir may decrease the level of some protease inhibitors in your blood. Your healthcare provider may need to adjust your dose of these medications as a result.
 
Cidofovir
Cidofovir may interfere with the kidneys' ability to remove emtricitabine and tenofovir from the blood. This could lead to increased blood levels of emtricitabine and tenofovir and increased risk of side effects. Check with your healthcare provider before taking these medications together.
(Drug Interactions With Emtricitabine and Tenofovir Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;