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More Medicines That Interfere With Efavirenz, Emtricitabine, and Tenofovir

Certain Benzodiazepines
Efavirenz, emtricitabine, and tenofovir can increase the level of certain benzodiazepine medications in the blood, possibly increasing the risk of side effects. With two of these medications (midazolam and triazolam), this interaction is so severe that they should never be taken with efavirenz, emtricitabine, and tenofovir.
 
Certain Seizure Medications
Taking efavirenz, emtricitabine, and tenofovir with certain seizure medications can decrease the level of both efavirenz, emtricitabine, and tenofovir and the seizure medication in your blood, possibly making them less effective. Your healthcare provider may need to adjust your dose of these medications as a result.
 
Cidofovir
Cidofovir may interfere with the kidneys' ability to remove efavirenz, emtricitabine, and tenofovir from the blood. This could lead to increased blood levels of efavirenz, emtricitabine, and tenofovir and increased risk of side effects. Check with your healthcare provider before taking these medications together.
 
Didanosine
Efavirenz, emtricitabine, and tenofovir can increase the level of didanosine in your blood. Your healthcare provider may need to lower your didanosine dosage to prevent this.
 
Diltiazem
Efavirenz, emtricitabine, and tenofovir can decrease the level of diltiazem in your blood, perhaps making it less effective. Your healthcare provider may need to increase your diltiazem dosage as a result.
 
Ergot Medications
Efavirenz, emtricitabine, and tenofovir should not be taken with ergot medications, due to the risk of life-threatening reactions.
 
Ganciclovir
Ganciclovir may interfere with the kidneys' ability to remove efavirenz, emtricitabine, and tenofovir from the blood. This could lead to increased blood levels of efavirenz, emtricitabine, and tenofovir and increased risk of side effects. Check with your healthcare provider before taking these medications together.

Info on Efavirenz, Emtricitabine, and Tenofovir

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