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Drugs That React With Efavirenz, Emtricitabine, and Tenofovir

Efavirenz, Emtricitabine, and Tenofovir Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when efavirenz, emtricitabine, and tenofovir is combined with any of the drugs listed above.
 
Adefovir
Adefovir may interfere with the kidneys' ability to remove efavirenz, emtricitabine, and tenofovir from the blood. This could lead to increased blood levels of the combination drug and increased risk of side effects of efavirenz, emtricitabine, and tenofovir. Check with your healthcare provider before taking these medications together.
 
Acyclovir
Acyclovir may interfere with the kidneys' ability to remove efavirenz, emtricitabine, and tenofovir from the blood. This could lead to increased blood levels of efavirenz, emtricitabine, and tenofovir and increased risk of side effects. Check with your healthcare provider before taking these medications together.
 
Atazanavir
Taking atazanavir and efavirenz, emtricitabine, and tenofovir together may affect the level of both medications in your blood. Your healthcare provider may need to increase your dose of these medications to prevent this interaction from occurring.
 
Certain Antibiotics or Antifungals
Combining efavirenz, emtricitabine, and tenofovir with certain antibiotics or antifungals may decrease the level of both the antibiotic or antifungal and the HIV medication in your blood. If you take efavirenz, emtricitabine, and tenofovir with one of these antibiotic or antifungal medications, your healthcare provider may need to adjust the dose of both medications. Efavirenz, emtricitabine, and tenofovir should never be combined with voriconazole, as combining these medications may make them both less effective.

Info on Efavirenz, Emtricitabine, and Tenofovir

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