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Serious Reactions to Depo-Provera

Serious Side Effects

Some Depo-Provera side effects are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
 
 
    • Vision or speech changes
    • Weakness or numbness in an arm or leg
    • A severe headache
 
  • Signs of a blood clot in the lung, such as:
 
    • Shortness of breath
    • Sudden chest pain
    • Coughing up blood
 
  • Signs of a blood clot in the leg, such as severe pain or swelling of the calf
  • Severe abdominal (stomach) pain
  • Signs of liver damage, such as:
 
    • Yellowing of the whites of the eyes or skin (jaundice)
    • Dark urine
    • Upper-right abdominal (stomach) pain
 
  • Seizures
  • Depression
  • Persistent abnormal menstrual periods or heavy vaginal bleeding
  • Injection site reactions, such as severe or persistent pain, pus, or bleeding
  • A change in blood glucose levels, especially if you have diabetes
  • Signs of an allergic reaction, such as:
 
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling
    • Difficulty breathing or swallowing.
 

Final Thoughts

You may experience some or none of the side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
 
Therefore, make sure to let your healthcare provider know if you develop any side effects while using Depo-Provera or if something "just does not seem right." While it may not be related to the medication, your healthcare provider will be able to diagnose and treat the problem.
Pregnancy and Pain

Depo-Provera Injection Information

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