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Depo-Provera Shot

A healthcare provider may prescribe Depo-Provera® (medroxyprogesterone intramuscular injection) for pregnancy prevention or relief from certain cancer symptoms. It comes as a liquid that is injected into a muscle every week to every three months, depending on the reason for using it.
The Depo-Provera shot contains medroxyprogesterone, which is a synthetic form of the hormone progesterone. Depo-Provera works to prevent pregnancy by stopping ovulation, thinning the endometrium, and thickening the cervical mucus. It can also help relieve symptoms associated with endometrial cancer or kidney cancer by slowing down the growth rate of cancer cells.
A healthcare provider will usually administer this shot. Depo-Provera is typically given in the muscle of the buttocks or upper arm.
(For more information on this shot, click Depo-Provera. This full-length article provides a complete overview of this drug, including specific uses, generic availability, and what your healthcare provider needs to know before you receive the injection.)
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