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More Info on Delavirdine Indications

How Does Delavirdine Work?

Delavirdine belongs to a group of HIV medications known as non-nucleoside reverse transcriptase inhibitors (NNRTIs). These medicines work by blocking a process that the HIV virus needs in order to multiply.
 
Like other viruses, HIV must use a person's own cells to reproduce. However, HIV is a little different from other viruses because it must first convert its genetic material from RNA to DNA. It is the DNA genes that allow HIV to multiply.
 
HIV converts its genetic material by using a special protein called the reverse transcriptase enzyme. To create DNA, this enzyme uses several different molecular building-blocks.
 
Delavirdine works by attaching to the reverse transcriptase enzyme, stopping it from making DNA. Without DNA, HIV cannot multiply. Delavirdine is not a cure for HIV or AIDS. It can help stop HIV from infecting healthy cells in the body, but it does not help cells that have already been infected with the virus.
 

is Delavirdine Used in Children?

Delavirdine is approved for use in adolescents as young as 16 years old. It is not approved for use in younger children. Talk with your child's healthcare provider about the benefits and risks of using the drug in children.
 

Is Delavirdine Used for Off-Label Reasons?

On occasion, your healthcare provider may recommend delavirdine for treating something other than HIV infection and AIDS. This is called an "off-label" use. At this time, delavirdine is used off-label to prevent HIV infection in people exposed to the HIV virus (such as a healthcare worker who comes in contact with a contaminated needle stick). This is called postexposure prophylaxis (PEP).
 

Delavirdine Drug Information

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