Side Effects of Darunavir

Headaches, high triglycerides, and high cholesterol are the most commonly reported side effects of darunavir. Other less common side effects, occurring in less than 2 percent of people, include fever, fatigue, and dry mouth. While darunavir side effects are typically minor, some are potentially serious and may require immediate medical attention, such as unusual bleeding, high blood sugar, or an allergic reaction.

Side Effects of Darunavir: An Introduction

As with any medicine, side effects are possible with darunavir ethanolate (Prezista™); however, not everyone who takes the drug will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with darunavir. Your healthcare provider can discuss a more complete list of darunavir side effects with you.)
 

Side Effects of Darunavir to Report

There are a number of side effects with darunavir that you should report to your healthcare provider. These include but are not limited to:
 
  • Signs of liver damage, such as:
 
    • Fatigue or a general ill feeling (malaise)
    • Loss of appetite
    • Nausea
    • Yellow eyes or skin (jaundice)
    • Tenderness near the liver (the upper-right abdomen)
    • Pale stools
 
  • High blood sugar (hyperglycemia)
  • Any unusual or unexplained bleeding
  • Changes in the distribution of fat on your body (such as a "buffalo hump")
  • Signs of an allergic reaction, such as:
 
    • Rash
    • Hives
    • Itching
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.
 

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(Side Effects of Darunavir Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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