Side Effects of Darunavir (Cont.)

Common Side Effects of Darunavir

Clinical studies have not evaluated darunavir alone for the treatment of HIV, since it is meant to be used along with other HIV medications. In fact, the available information on side effects involves studies that used darunavir plus one or two other HIV medications. Therefore, it is difficult to determine whether these side effects are caused by darunavir or the other HIV medications.
 
Based on these studies, the most common side effects of darunavir (plus one or two other HIV medications) included:
 

Less Common Side Effects of Darunavir

Rare side effects of darunavir occur in less than 2 percent of people taking the drug. Because these side effects are so uncommon, it is difficult to determine if they are actually caused by darunavir or something else.
 
These less common side effects include but are not limited to:
 
  • Fever
  • Fatigue
  • Water retention in the calves, ankles, or feet
  • High blood pressure (hypertension)
  • Gas
  • Dry mouth
  • Indigestion or heartburn
  • Nausea
  • Osteoporosis
  • Drowsiness
  • Unusual sensations (like burning, tingling, or numbness) in the hands or feet
  • Eczema
  • Increased sweating
  • A spinning sensation (vertigo).
     

Final Thoughts on Side Effects of Darunavir

You may experience some or none of the side effects of darunavir listed in this article. Unfortunately, it can be difficult to tell whether any particular side effect (such as nausea) is actually caused by darunavir or other factors. Therefore, make sure to let your healthcare provider know if you develop any side effects while taking the drug or if something "just does not seem right." While it may not be a side effect of darunavir, your healthcare provider will be able to diagnose and treat the problem.
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;