Darunavir Dosing: An Introduction
The dose of
darunavir ethanolate (
Prezista™) that your healthcare provider recommends will vary, depending on a number of factors, including:
- Your age
- Whether or not you have taken other HIV medications before
- Other medical conditions you may have
- Other medications you may be taking.
As always, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
Darunavir Dosing for Adults
Darunavir is always combined with
ritonavir (
Norvir®), another HIV medication that increases the level of darunavir in the blood and helps it work better.
The recommended dose of darunavir for treating adults with HIV or
AIDS who have already taken HIV medications before ("treatment-experienced" individuals) is darunavir 600 mg (two 300-mg tablets) twice daily with food, taken with ritonavir 100 mg twice daily.
For adults who have not taken HIV medications before ("treatment-naïve" individuals), the recommended darunavir dosage is 800 mg (two darunavir 400 mg tablets) taken once a day with food, combined with ritonavir once daily.
Darunavir Dosage for Children
Darunavir is also approved for treating HIV and AIDS in children age 6 to 18 years old. The recommended dosage varies, depending on the child's weight.
For children weighing 44 to 65 pounds, the recommended dosage is darunavir 375 mg twice daily with food plus ritonavir 50 mg twice daily.
For children weighing 66 to 87 pounds, the recommended dosage is darunavir 450 mg twice daily with food plus ritonavir 100 mg twice daily.
For children weighing 88 pounds or more, the recommended dosage is darunavir 600 mg twice daily with food plus ritonavir 100 mg twice daily.
