Darunavir Dosing

For the treatment of HIV and AIDS, the recommended darunavir dosage is 600 mg, taken twice a day with food and with 100 mg of ritonavir. Taking the medication without food or ritonavir will decrease the level of darunavir in your blood, making it less effective. Therefore, to help ensure the effectiveness of darunavir, dosing guidelines must be followed carefully.

 

Darunavir Dosing: An Introduction

The dose of darunavir ethanolate (Prezista™) that your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • Other medical conditions you may have
  • Other medications you may be taking.
     
As always, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
 

Darunavir Dosing for HIV and AIDS

Darunavir is always combined with ritonavir (Norvir®), another HIV medication that increases the level of darunavir in the blood and helps it work better. The recommended dose of darunavir for treating adults with HIV or AIDS is darunavir 600 mg (two 300-mg tablets) twice daily with food, taken with ritonavir 100 mg twice daily.
 

General Information on Dosing With Darunavir

Considerations for people taking darunavir include the following:
 
  • The medication comes in tablet form. It is usually taken by mouth twice daily.
     
  • Darunavir should be taken with food.
     
  • Try to take darunavir at the same times every day to maintain an even level in your blood.
     
  • For the medication to work properly, it must be taken as prescribed. It is very important that you closely follow your healthcare provider's instructions about taking darunavir. Missing doses can increase the chance of the virus developing resistance to the medication, thereby making it less effective.
     
  • If you are unsure about anything related to darunavir dosing, talk to your doctor, nurse, or pharmacist. Do not stop taking the drug without first discussing it with your healthcare provider.
     
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;