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More Info on Amprenavir Indications

How Does Amprenavir Work?

Amprenavir is part of a group of HIV medications known as protease inhibitors. These medicines work by blocking a process that the HIV virus needs in order to multiply.
 
Like other viruses, HIV must use a person's own cells to reproduce. Once inside an infected cell, the HIV virus uses the cell to make DNA, which enables it to make new viruses that can spread to other cells. The DNA is made in long strands that must be clipped into shorter, usable strands using enzymes called proteases.
 
Amprenavir is a protease inhibitor, which means that it stops protease enzymes from clipping DNA into shorter strands. Because the long, unclipped DNA strands cannot be used to make new viruses, this helps to stop the spread of HIV to uninfected cells. The medication is not a cure for HIV or AIDS, however. Although amprenavir can help prevent the HIV virus from infecting healthy cells in the body, it cannot help cells that have already been infected.
 

Is Amprenavir Used in Children?

Amprenavir is approved for treating HIV and AIDS in children as young as four years old. Amprenavir oral solution should never be used in children younger than four years old, due to the risk of poisoning from one of the inactive ingredients (propylene glycol), even when it is used at normal doses. Talk with your child's healthcare provider about the benefits and risks of using the drug in children.
 

Is Amprenavir Used for Off-Label Reasons?

On occasion, your healthcare provider may recommend amprenavir for treating something other than HIV infection and AIDS. This is called an "off-label" use. At this time, amprenavir is used off-label to prevent HIV infection in people exposed to the virus (such as a healthcare worker who comes in contact with a contaminated needle stick). This is called postexposure prophylaxis (PEP).
 

Amprenavir Drug Information

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