Drug Interactions With Abacavir/Lamivudine

Some of the medications that may cause drug interactions with abacavir/lamivudine include methadone, valganciclovir, and ribavirin. These negative interactions could increase your risk of side effects and affect the level of abacavir/lamivudine in your blood. To help prevent abacavir/lamivudine drug interactions, be sure to tell your healthcare provider about all other medicines you are taking.

 

Abacavir/Lamivudine Drug Interactions: An Introduction

Abacavir/lamivudine (Epzicom™) can potentially interact with several other medicines. Some of these medicines that may lead to abacavir/lamivudine interactions include:
 
  • Alcohol
  • Ganciclovir (Cytovene®)
  • Interferon medications, such as:

 

    • Interferon alfa-2a (Roferon®-A)
    • Interferon alfa-2b (Intron® A)
    • Interferon alfa-2b and ribavirin (Rebetron®)
    • Interferon alfa-n3 (Alferon® N)
    • Interferon alfacon-1 (Infergen®)
    • Interferon beta-1a (Avonex®, Rebif®)
    • Interferon beta-1b (Betaseron®)
    • Interferon gamma-1b (Actimmune®)
    • Peginterferon alfa-2a (Pegasys®)
    • Peginterferon alfa-2b (PEG-Intron®)

 

  • Methadone (Dolophine®, Methadose®)
  • Ribavirin (Copegus®, Rebetol®, Ribasphere®, Virazole®)
  • Trimethoprim and sulfamethoxazole (Bactrim®, Septra®)
  • Valganciclovir (Valcyte™)
  • Zalcitabine (Hivid®).
     
(Drug Interactions With Abacavir/Lamivudine Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;