Drug Interactions With Abacavir/Lamivudine
Some of the medications that may cause drug interactions with abacavir/lamivudine include methadone, valganciclovir, and ribavirin. These negative interactions could increase your risk of side effects and affect the level of abacavir/lamivudine in your blood. To help prevent abacavir/lamivudine drug interactions, be sure to tell your healthcare provider about all other medicines you are taking.
Abacavir/lamivudine (Epzicom™) can potentially interact with several other medicines. Some of these medicines that may lead to abacavir/lamivudine interactions include:
- Ganciclovir (Cytovene®)
- Interferon medications, such as:
- Interferon alfa-2a (Roferon®-A)
- Interferon alfa-2b (Intron® A)
- Interferon alfa-2b and ribavirin (Rebetron®)
- Interferon alfa-n3 (Alferon® N)
- Interferon alfacon-1 (Infergen®)
- Interferon beta-1a (Avonex®, Rebif®)
- Interferon beta-1b (Betaseron®)
- Interferon gamma-1b (Actimmune®)
- Peginterferon alfa-2a (Pegasys®)
- Peginterferon alfa-2b (PEG-Intron®)
- Methadone (Dolophine®, Methadose®)
- Ribavirin (Copegus®, Rebetol®, Ribasphere®, Virazole®)
- Trimethoprim and sulfamethoxazole (Bactrim®, Septra®)
- Valganciclovir (Valcyte™)
- Zalcitabine (Hivid®).
The following sections explain in detail the potentially negative interactions that can occur when abacavir/lamivudine is combined with any of the drugs listed above.